STRINGSTRING
CDM68101.1 CDM68101.1 CDM68102.1 CDM68102.1 CDM69864.1 CDM69864.1 yjbM yjbM rpoC rpoC rpoB rpoB cheR cheR CDM69074.1 CDM69074.1 CDM67520.1 CDM67520.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
CDM68101.1RNA polymerase recruits alternative sigma factors as a means of switching on specific regulons. Most bacteria express a multiplicity of sigma factors. Two of these factors, sigma-70 (gene rpoD), generally known as the major or primary sigma factor, and sigma-54 (gene rpoN or ntrA) direct the transcription of a wide variety of genes. The other sigma factors, known as alternative sigma factors,are required for the transcription of specific subsets of genes; Family membership. (186 aa)    
Predicted Functional Partners:
CDM68102.1
Putative membrane protein.
       0.773
CDM69864.1
RNA polymerase recruits alternative sigma factors as a means of switching on specific regulons. Most bacteria express a multiplicity of sigma factors; High confidence in function and specificity; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.768
yjbM
GTP pyrophosphokinase YjbM; Functions as a (p)ppGpp synthase. In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. YjbM has probably a minor role in stringent response; High confidence in function and specificity.
       0.508
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.494
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.486
cheR
CheR proteins are part of the chemotaxis signaling mechanism in bacteria. CheR methylates the chemotaxis receptor at specific glutamate residues. CheR is an S-adenosylmethionine-dependent methyltransferase -the C-terminal domain (this one) binds SAM; High confidence in function and specificity.
    
   0.465
CDM69074.1
The protein kinase domain is a structurally conserved protein domain containing the catalytic function of protein kinases.[2][3][4] Protein kinases are a group of enzymes that move a phosphate group onto proteins, in a process called phosphorylation. This functions as an on/off switch for many cellular processes, including metabolism,transcription, cell cycle progression,cytoskeletal rearrangement and cell movement, apoptosis,and differentiation; Family membership.
 
 
 
 0.424
CDM67520.1
Members of this family are transcriptional regulators that appear to be related to the PF01047 family. This family includes PadR Q9EXE6 a protein that is involved in negative regulation of phenolic acid metabolism; Family membership.
  
    0.405
Your Current Organism:
Clostridium bornimense
NCBI taxonomy Id: 1216932
Other names: C. bornimense, CECT 8097, Clostridium bornimense Hahnke et al. 2014, Clostridium sp. M2/40, DSM 25664, strain M2/40
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